4-aminobenzoic acid
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| 4-aminobenzoic acid | |
|---|---|
| Names: | 4-aminobenzoic acid para-aminobenzoic acid vitamin B10 PABA |
| Formula: | NH2C6H4COOH |
| Molar mass: | 137.138 g/mol |
| Density: | 1.374 g/cm3 (α-form) 1.39 g/cm3 (β-form) 1.43 g/cm3 (γ-form) 1.48 g/cm3 (δ-form) |
| Crystal system: | monoclinic (α-form) a=18.571 Å, b=3.843 Å, c=18.632 Åα=90°, β=93.67°, γ=90° monoclinic (β-form) a=6.278 Å, b=8.583 Å, c=12.365 Åα=90°, β=100.13°, γ=90° cubic (γ-form) a=26.9945 Å, b=26.9945 Å, c=26.9945 Åα=90°, β=90°, γ=90° monoclinic (δ-form) a=6.4341 Å, b=4.6151 Å, c=10.5313 Åα=90°, β=100.73°, γ=90° |
| Shapes: | |
| Color: | white |
| Melting point: | 187 °C460.15 K <br />368.6 °F <br />828.27 °R <br /> |
| Stability: | stable |
| Hardness: | fragile |
| Toxicity: | slightly toxic LD50=1000mg/kg |
Description
Organic compound, monobasic aromatic aminoacid. Doesn't form water hydrates.
Can be bought in pharmacy (as vitamin B10 - in form of pills).
Influence of temperature
Due to low solubility in water, it's easier to grow crystals by cooling the solution.
Can be easily separated from insoluble impurities containing in the pharmacy pills by dissolving in hot water and filtration.
| Temperature | g/100,00 g water | g/100,00 g ethanol | g/100,00 g diethyl ether | g/100,00 g benzene | g/100,00 g dioxane | g/100,00 g 1-butanol |
|---|---|---|---|---|---|---|
| 18°C291.15 K <br />64.4 °F <br />524.07 °R <br /> | 0.495 | |||||
| 20°C293.15 K <br />68 °F <br />527.67 °R <br /> | 12 | 2 | ||||
| 25°C298.15 K <br />77 °F <br />536.67 °R <br /> | 0.5 | 0.07 | 11.71 | 6 | ||
| 30°C303.15 K <br />86 °F <br />545.67 °R <br /> | 0.611 | 0.35 | ||||
| 37°C310.15 K <br />98.6 °F <br />558.27 °R <br /> | 0.84 |
Gallery
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Recrystallized vitamin B10 pills4-aminobenzoic acid, Mailinmypocket, Sciencemadness forumSciencemadness forum
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Recrystallized vitamin B10 pills4-aminobenzoic acid, Mailinmypocket, Sciencemadness forumSciencemadness forum
Sources
- R.A.Kiper Properties of compounds. Handbook
- S. Athimoolam, S. Natarajan, 4-Carboxyanilinium (2R,3R)-tartrate and a redetermination of the α-polymorph of 4-aminobenzoic acid
- S. Gracin, A. Fischer, Redetermination of the β-polymorph of p-aminobenzoic acid
- R. Benali-Cherif, R. Takouachet, E.-E. Bendeif, N. Benali-Cherif, The structural properties of a noncentrosymmetric polymorph of 4-aminobenzoic acid
- M. R. Ward, S. Younis, A. J. Cruz-Cabeza, C. L. Bull, N. P. Funnell, I. D. H. Oswald, Discovery and recovery of delta p-aminobenzoic acid
- C. Y. MaKevin J. Roberts, Molecular, Crystal, and Surface Chemistry of p-Aminobenzoic Acid and the Interrelationship between Its Solution-Phase Crystallization and Solid-Form Selectivity
- M. N. Hussain, L. V. Meervelt, T. V. Gerven, Crystallization of para-aminobenzoic acid forms from specific solvents
